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Clofazimine is taken to treat leprosy (Hansen's disease). It is sometimes given with other medicines for leprosy. When clofazimine is used to treat "flare-ups'' of leprosy, it may be given with a cortisone-like medicine. Clofazimine is used together with other medicines to treat a form of leprosy (also known as Hansen's disease), called lepromatous leprosy, including dapsone-resistant lepromatous leprosy, and lepromatous leprosy complicated by erythema nodosum leprosum.

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